In recent years, doctors have regularly treated patients suffering from depression with Effexor, a drug manufactured by Wyeth, as well as patients with generalized anxiety disorder and social affective disorder. In the 16 years since Effexor was approved by the U.S. Food & Drug Administration ("FDA") and has been widely prescribed by doctors, some patients taking Effexor have claimed to have increased suicide risks. This increase in suicidal tendencies as the result of taking Effexor caused the FDA to issue warnings regarding its usage in 2004 and 2005. Effexor is also thought to cause a disorder commonly referred to as serotonin syndrome, which results from the interaction of Effexor with some medications used to treat migraine headaches. The risk of developing serotonin syndrome was announced by the FDA in 2006. The FDA continues to work with drug companies to monitor the risk of suicidal behavior caused by antidepressants such as Effexor through research and studies.